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Department of Medical Imaging and Radiological Science

 
 
:::

Fang-Hsin Chen

 

 

董傳中

Name:

Fang-Hsin Chen

Title :

Assistant Professor

Education:

Ph.D., National Tsing Hua University, Taiwan

TEL & Mail:

03 - 2118800 # 3838

fanghsinchen@mail.cgu.edu.tw

Research Interest 

  • Tumor microenvironment
  • Tumor angiogenesis and anti-angiogenic agent

  • Immunotherapy

  • Medical Imaging for range verification in proton therapy

  • Metabolic changes after radiotherapy in tumor and normal tissues

Instruction Courses :

  • Radiobiology

(一)     Publishments

1. Gene Expression Profiling of Tumor-Associated Macrophages after Exposure to Single-Dose Irradiation

   Wei Hsiang Kung, Ching Fang Yu, Andy Chi Lung Lee, Chi Dung Yang, Fang  

   Hsin Chen and Hsien Da Huang

 Computational Biology and Chemistry (accepted, co-corresponding)

2. Diffusion Radiomics Analysis of Intratumoral Heterogeneity in a Murine Prostate Cancer Model Following Radiotherapy: Pixelwise Correlation With Histology

Lin YC, Lin G, Hong JH, Chen FH, Ng SH, Wang CC.

    J. MAGN. RESON. IMAGING 2017 Feb 8. (Epub ahead of print)

3. Flow versus Permeability Weighting in Estimating the Forward Volumetric Transfer Constant (Ktrans) Obtained by DCE-MRI with Contrast Agents of Differing Molecular Sizes.

   Cheng-He Li, Fang-Hsin Chen, Dawid Schellingerhout, Yu-Shi Lin, Ji-Hong 

   Hong and Ho-Ling Liu.

   Magnetic Resonance Imaging. 2017, 36: 105-111 (co-first author) (SCI)

4.      Decline of Tumor Vascular Function as Assessed by DCE-MRI is Associated with Poor Responses to Radiotherapy and Chemotherapy.

F. H. Chen, C. C. Wang, H. L. Liu, S. Y. Fu, C. F. Yu, C. Chang, C. S. Chiang and J. H. Hong 

Int. J. Radiat. Oncol. Biol. Phys. 2016, 95:1495-1503 (SCI)

5.  Effects of indirect actions and oxygen on relative biological effectiveness: estimate of DSB induction and conversion induced by gamma rays and helium ions

   Ju-Ying Tsa, Fang-Hsin Chen, Tsung-Yu Hsieh and Ya-Yun Hsiao

   Journal of Radiation Research, 2015, pp. 1–9 (SCI)

6.  Effects of pre-irradiation and SDF-1 suppression on the progression of murine astrocytoma  

   cells grown in different stromal beds

Ching-Fang Yu, Chi-Min Lin, Shu-Chi Wang, Fang-Hsin Chen, Ji-Hong Hong, Chien-Sheng Tsai, Ying-Chieh Yang , and Chi-Shiun Chiang.

International Journal of Radiation Biology 2014 Dec;90(12):1162-8. (SCI)

7.  Combination of Vessel-targeting Agents with Fractionated Radiotherapy: 

    The Role of SDF-1/CXCR4 Pathway

    Fang-Hsin Chen, Ji-Hong Hon, Sheng-Yung Fu, Chun-Chieh Wang and Chi-Shiun Chiang

    Int. J. Radiation Oncology Biol. Phys.; 2013, 86(4), 777–784  (SCI)

8. Irradiation promotes an M2 macrophage phenotype in tumor hypoxia

    Chi-Shiun ChiangSheng Yung FuShu-Chi WangChing-Fang YuFang-Hsin ChenChi-Min Lin and Ji-Hong Hong

Frontiers in Oncology; 2012, 2, article 89  (SCI)

9. In vivo imaging of radiation-induced tissue apoptosis by 99mTc(I)-his6-annexin A5

   Kun-Ju Lin, Chun-Chung Wu, Yi-Hsin Pan, Fang-Hsing Chen, Sheng-Yung Fu,

   Chi-Shiun Chiang, Ji-Hong Hong, Jem-Mau Lo

   ANNALS OF NUCLEAR MEDICINE; 2012, 26, 272-280 (SCI)

10.  Vaculatures in tumors growing from preirradiated tissues : formed by vasculogenesis and resistant to radiation and anti-angiogenic therapy, 

Chen FH, Chiang CS, Wang CC, Fu SY, Tsai CS, Jung SM, Weng CJ, Lee CC and Hong JH.

    Int. J. Radiation Oncology Biol. Phys.; 2011, 80(5), 1512–21 (SCI)

11.  Radiotherapy Decreases Vascular Density and Causes Hypoxia with Macrophage Aggregation in TRAMP-C1 Prostate Tumors

Fang-Hsin Chen, Chi-Shiun Chiang, Chun-Chieh Wang, Chien-Sheng Tsai, Shih-MingJung, Chung-Chi Lee, William H.McBride, and Ji-Hong Hong

Clinical Cancer Research 2009; 15(5), 1721-1729(SCI)

12.  Macrophages from Irradiated Tumors Express Higher Levels of iNOS, Arginase-I and COX-2, and Promote Tumor Growth

CHIEN-SHENG TSAI, FANG-HSIN CHEN, CHUN-CHIEH WANG,

HSIANG-LING HUANG, SHIH-MING JUNG, CHI-JUNG WU,

CHUNG-CHI LEE, WILLIAM H. MCBRIDE, CHI-SHIUN CHIANG, AND

JI-HONG HONG.

Int. J. Radiation Oncology Biol. Phys.; 2007, 68(2), 499–507 (SCI)

13.  Compartmental Responses after Thoracic Irradiation of Mice: Strain

Differences

CHI-SHIUN CHIANG, WEI-CHUNG LIU, SHIH-MING JUNG, FANG-HSIN CHEN, CHI-RONG WU, WILLIAM H. MCBRIDE, CHUNG-CHI LEE, AND JI-HONG HONG

Int. J. Radiation Oncology Biol. Phys.; 2005, 62 (3), 862–871(SCI) 

14.  Brochoalveolar lavage and interstitial cells have different roles in   

   radiation-induced lung injury

Ji-Hong Hong, Shih-Ming Jung, Thomas Chang Yao Tsao, Chi-Jung Wu, Chin-Yi Lee, Fang-Hsin Chen, Chung-Hsin Hsu, William H. Mcbride and Chi-Shiun Chiang

Int. J. Radiation Oncology Biol. Phys.; 2003, 79 (3), 159-167 (SCI)

 

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